For practitioner dispensing and professionally guided use.
Always read the label and follow the directions for use.
Contraindicated during pregnancy.
Do not use while breastfeeding.
Do not give Golden Seal directly to newborns or infants.
Golden Seal contains berberine, which may cause or worsen jaundice in newborn infants and may contribute to a dangerous accumulation of bilirubin.
Do not use where neonatal jaundice is present.
The current official manufacturer page also lists high blood pressure as a contraindication. Confirm this against the Australian bottle label and obtain professional advice before use if you have high or unstable blood pressure.
Consult your healthcare practitioner or pharmacist before use if you take any prescription medicine.
Golden Seal can affect the way the body processes numerous medicines by inhibiting the CYP2D6 and CYP3A4 metabolic pathways. This gives it a comparatively high potential for medication interactions.
Professional review is particularly important with medicines that have a narrow therapeutic range, sedatives, anaesthetic medicines and medicines affected by CYP2D6 or CYP3A4.
MediHerb’s current interaction guidance advises monitoring with midazolam because Golden Seal may increase its level.
Consult your prescribing practitioner before use with metformin. A clinical study found that Golden Seal reduced metformin levels by approximately 25%, which could interfere with blood-glucose management.
Do not use Golden Seal as a substitute for antibiotics, infection testing, prescribed respiratory treatment, diabetes medication or medical assessment.
Long-term safety has not been established. Golden Seal is better suited to targeted, professionally directed use than indefinite daily supplementation.
Do not place the undiluted extract directly into the eyes.
Eye pain, vision changes, light sensitivity, significant discharge or persistent redness requires professional assessment rather than home treatment with an herbal eye bath.
Seek medical advice for persistent fever, breathing difficulty, chest pain, worsening respiratory symptoms or symptoms that do not improve.
Seek medical advice for ongoing diarrhoea, fever, blood or mucus in the stool, unexplained weight loss or diarrhoea occurring at night.
Vomiting blood, passing black stools or significant rectal bleeding requires urgent medical assessment.
Discontinue use at least seven days before general anaesthesia, surgery or an invasive dental procedure unless otherwise directed by your treating healthcare professional.
Stop use and seek professional advice if significant nausea, vomiting, constipation, diarrhoea, abdominal pain, jaundice or another unexpected reaction occurs.
Contains ethanol.
Keep out of reach of children.