Orthoplex Methyl1c BioEnhanced is a practitioner-grade activated methylation support formula. It combines active folate, methylated and hydroxylated forms of vitamin B12, activated B vitamins, zinc and vitamin C to support energy production, nervous system health and methylation-related nutrient pathways.

Orthoplex Methyl1c BioEnhanced is not a basic B-complex. It contains Metafolin, a patented form of L-5-MTHF, along with methylcobalamin, hydroxocobalamin, pyridoxal-5-phosphate, riboflavin sodium phosphate, zinc and vitamin C. This makes it more targeted for methylation and homocysteine support.

Orthoplex Methyl1c BioEnhanced helps reduce homocysteine levels, maintain energy production, aid neurotransmitter synthesis, support a healthy stress response, and support nervous system and immune system health.

Metafolin is a patented form of L-5-MTHF, which is an active folate form. It is included to support folate-dependent processes such as methylation, homocysteine metabolism, healthy growth and development, and normal nervous system function.

Yes. Orthoplex Methyl1c BioEnhanced contains methylcobalamin, also known as methyl B12, as well as hydroxocobalamin. These vitamin B12 forms are included to support energy production, nervous system health and methylation-related pathways.

Yes. Orthoplex Methyl1c BioEnhanced is formulated to help reduce homocysteine levels. Homocysteine should be interpreted in context, so customers with known high homocysteine, cardiovascular concerns or abnormal blood results should seek professional guidance.

Some people can feel more alert, energised or overstimulated when using methylated B vitamins, especially if they are sensitive to methylfolate or methyl B12. If you feel wired, anxious, unsettled or uncomfortable, stop use and speak with a qualified health professional.

The adult dose is 1 capsule daily with food, or as recommended by your registered healthcare practitioner. Always follow the product label and avoid taking more than directed.

Yes. Orthoplex Methyl1c BioEnhanced contains vitamin B6. Stop taking this product and speak with your healthcare practitioner as soon as possible if you experience tingling, burning or numbness.

No. This information is general only and does not replace personalised medical advice. If symptoms persist, or if you are pregnant, breastfeeding, taking medication, shopping for a child, managing anxiety, mood concerns, high homocysteine, cardiovascular concerns, neurological symptoms or a diagnosed condition, speak with a qualified health professional before use.