Folate 400 supports healthy methylation, DNA synthesis, gene regulation, cellular health, nervous system function and cardiovascular health.

Each capsule provides 400 mcg of L-5-methyltetrahydrofolate as Metafolin®. This is a metabolically active form of folate.

No. Folic acid must be converted through several metabolic steps before the body can use it. L-5-MTHF is already in an active folate form and does not require activation by the DHFR or MTHFR enzymes.

L-5-MTHF does not require conversion by the MTHFR enzyme. However, an MTHFR result alone does not determine whether supplementation is needed or what dose is appropriate.

Folate contributes to normal DNA synthesis, healthy cell division, red blood cell formation, methylation and nervous system function. It also works with vitamins B6 and B12 in homocysteine metabolism.

Anyone planning pregnancy, pregnant or breastfeeding should consult a healthcare professional before using it. Folate 400 contains methylfolate, while Australian pregnancy guidance specifically recommends folic acid before conception and during early pregnancy. It should not automatically replace a prenatal supplement.

Take one capsule once or twice daily with meals, unless otherwise directed by a healthcare professional.

A 90-capsule bottle provides approximately 45–90 days, depending on whether one or two capsules are taken daily.

Yes. The manufacturer identifies it as vegetarian and vegan. The formula contains hypoallergenic plant fibre and a vegetarian cellulose capsule and is free from gluten, dairy and soy ingredients.

Consult a healthcare professional if you have a medical condition, take medication or are pregnant or breastfeeding. Professional advice is especially important if you take methotrexate, anticonvulsants or other medicines that affect folate metabolism, or if vitamin B12 deficiency is suspected.